Drying is the last step in the production of tablets from the extraction of raw materials to the semi-finished products of dry paste. The application of drying equipment and technology is directly related to product quality. In the production of tablets, the other links are even better controlled. If there are problems such as uneven drying, destruction of active ingredients, and thermal deterioration during the drying process, the quality of the tablets will eventually be at a loss.
The vacuum continuous drying equipment and technology have the advantages of low temperature drying, less destruction of active ingredients, looseness, easy dissolution, absorption, drying, and sterilization, so as to ensure high active ingredient, high sterility index, and good oral absorption. Therefore, the vacuum continuous drying method has many unique advantages compared with currently used oven drying methods, spray drying methods, etc., and can guarantee that the product quality is much higher than that of other drying methods.
The vacuum continuous drying method has the following four main characteristics: Low-temperature drying In the vacuum environment, the boiling point of moisture is reduced, and low-temperature drying can be achieved, which provides favorable conditions for the drying of heat-sensitive materials and can effectively avoid the active ingredients of the products during the drying process. Destroyed by high temperatures. In the production of natural extract products, the product is in a vacuum, closed environment throughout the drying process, and the drying process is mild (temperature 40 °C ~ 60 °C), which can maintain its active ingredients to the maximum extent possible.
Oxygen-differentiated vacuum environment, the oxygen partial pressure is reduced, to avoid the phenomenon of material degradation in the drying process, to protect the quality of the product being dried. Loose micropores Under high vacuum conditions, after the product has been gradually dried over a period of time, there are micropores in the microscopic structure, and after the particles are directly crushed to a desired particle size, the particles have good fluidity.
At the same time, due to the microscopic loose structure, the particles are extremely fast-dissolving and are more conducive to human body absorption. Simultaneous sterilization in the vacuum hypoxia state, can effectively inhibit the proliferation of bacteria to achieve the purpose of killing bacteria. While drying the product, sterilization can be achieved again. Double sterilization ensures that the product is aseptic.
The vacuum continuous drying equipment and technology have the advantages of low temperature drying, less destruction of active ingredients, looseness, easy dissolution, absorption, drying, and sterilization, so as to ensure high active ingredient, high sterility index, and good oral absorption. Therefore, the vacuum continuous drying method has many unique advantages compared with currently used oven drying methods, spray drying methods, etc., and can guarantee that the product quality is much higher than that of other drying methods.
The vacuum continuous drying method has the following four main characteristics: Low-temperature drying In the vacuum environment, the boiling point of moisture is reduced, and low-temperature drying can be achieved, which provides favorable conditions for the drying of heat-sensitive materials and can effectively avoid the active ingredients of the products during the drying process. Destroyed by high temperatures. In the production of natural extract products, the product is in a vacuum, closed environment throughout the drying process, and the drying process is mild (temperature 40 °C ~ 60 °C), which can maintain its active ingredients to the maximum extent possible.
Oxygen-differentiated vacuum environment, the oxygen partial pressure is reduced, to avoid the phenomenon of material degradation in the drying process, to protect the quality of the product being dried. Loose micropores Under high vacuum conditions, after the product has been gradually dried over a period of time, there are micropores in the microscopic structure, and after the particles are directly crushed to a desired particle size, the particles have good fluidity.
At the same time, due to the microscopic loose structure, the particles are extremely fast-dissolving and are more conducive to human body absorption. Simultaneous sterilization in the vacuum hypoxia state, can effectively inhibit the proliferation of bacteria to achieve the purpose of killing bacteria. While drying the product, sterilization can be achieved again. Double sterilization ensures that the product is aseptic.
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